2-Butoxyethanol – wikipedia gas in back shoulder

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In 2006, the European production of butyl glycol electricity symbols ks3 ethers amounted to 181 kilo tons, of which approximately 50% (90 kt/a) was 2-Butoxyethanol. World production is estimated to be 200 to 500 kt/a, of which 75% is for paints and coatings [6] and 18% for metal cleaners and household cleaners. [7] In the US, it is considered a High Production Volume Chemical because greater than 100 million pounds of this chemical is produced per year. [7] Uses [ edit ]

2-Butoxyethanol is a glycol ether with modest surfactant properties (and it can be used as a mutual solvent). In use since the 1930s, glycol ethers are solvents that dissolve both water-soluble and hydrophobic substances. Glycol ethers consist of two components, an alcohol and ether. According to the nature of alcohol, molecules of this class can be divided into two groups: E series and P series which correspond to ethylene and propylene respectively. Glycol ethers are selected for specific purposes, such as solubility, inflammability, and volatility. [8] Commercial uses [ edit ]

2-Butoxyethanol is a solvent for paints and surface coatings, as well as cleaning products and inks. [6] [9] Products that contain 2-butoxyethanol include acrylic resin formulations, asphalt release agents, firefighting foam, leather protectors, oil spill dispersants, degreaser applications, photographic strip solutions, whiteboard cleaners, liquid soaps, cosmetics, dry cleaning solutions, lacquers, varnishes, herbicides, latex paints, enamels, printing paste, and varnish removers, and silicone caulk. Products containing this compound are commonly found at construction sites gas exchange in the lungs happens by the process of, automobile repair shops, print shops, and facilities that produce sterilizing and cleaning products. It is the main ingredient of many home, commercial and industrial cleaning solutions. Since the molecule has both non-polar and polar ends, butoxyethanol is useful for removing both polar and non-polar substances, like grease and oils. It is also approved by the U.S. FDA to be used as direct and indirect food additives, which include antimicrobial agents, defoamers, stabilizers, and adhesives. [10] In the petroleum industry [ edit ]

In the petroleum industry, 2-butoxyethanol is a component gas x and pregnancy of fracturing fluids, drilling stabilizers, and oil slick dispersants for both water-based and oil-based hydraulic fracturing [7] [ clarification needed] When liquid is pumped into the well, the fracturing fluids are pumped under extreme pressure, so 2-butoxyethanol is used to stabilize them by lowering the surface tension. [7] As a surfactant, 2-butoxyethanol adsorbs at the oil-water interface of the fracture. [12] The compound is also used to facilitate the release of the gas by preventing congealing. [7] It is also used as a crude oil-water coupling solvent for more general oil well workovers. [7] Because of its surfactant properties, it is a major constituent (30–60% w/w) in the oil spill dispersant gas station car wash Corexit 9527, [13] which was widely used in the aftermath of the 2010 Deepwater Horizon oil spill. [10] Safety [ edit ]

2-Butoxyethanol has a low acute toxicity, with LD 50 of 2.5 g/kg in rats. [6] Laboratory tests by the U. S. National Toxicology Program have shown that only sustained exposure to high concentrations (100-500 ppm) of 2-butoxyethanol can cause adrenal tumors in animals. [14] American Conference of Governmental Industrial Hygienists (ACGIH) reports that 2-butoxyethanol is carcinogenic in rodents. [15] These rodent tests may not directly translate to carcinogenicity in humans, as the observed mechanism of cancer involves the rodents’ forestomach, which humans lack. [16] OSHA does not regulate 2-butoxyethanol as a carcinogen. [17] 2-butoxyethanol has not been shown to penetrate shale rock in a study conducted by Manz. [18]

2-Butoxyethanol can be disposed of by incineration. It was shown that disposal occurs faster in the presence of semiconductor particles. [3] 2-Butoxyethanol usually decomposes in the presence of air within a few days by reacting with oxygen radicals. [20] It has not been identified gas key staking tool as a major environmental contaminant, nor is it known to bio-accumulate. [21] 2-Butoxyethanol biodegrades in soils and water, with a half life of 1–4 weeks in aquatic environments. [10] Human exposure [ edit ]

2-butoxyethanol most commonly enters the human body system through dermal absorption, inhalation, or oral consumption of the chemical. [3] The ACGIH threshold limit value (TLV) for worker exposure is 20 ppm, which is well above the odor detection threshold of 0.4 ppm. Blood or urine concentrations of 2-butoxyethanol or the metabolite 2-butoxyacetic acid may be measured using chromatographic techniques. A biological exposure index of 200 mg 2-butoxyacetic acid per g creatinine has been established in an end-of-shift urine specimen for U.S. employees. [22] [23] 2-Butoxyethanol and its metabolites fall to undetectable levels in urine after about 30 hours in human males. [24] Animal studies [ edit ]

Harmful effects have been observed in nonhuman mammals exposed to high levels of 2-butoxyethanol. Developmental effects were seen in a study that exposed pregnant Fischer 344 rats, a type of laboratory rat o goshi technique, and New Zealand white rabbits to varying doses of 2-butoxyethanol. At 100 ppm (483 mg/m 3) and 200 ppm (966 mg/m 3) exposure, statistically significant increases were observed in the number of litters with skeletal defects. Additionally, 2-butoxyethanol was associated with a significant decrease in maternal body weight, uterine weight, and number of total implants. [25] 2-Butoxyethanol is metabolized in mammals by the enzyme alcohol dehydrogenase. [24]

When exposed to 2-butoxyethanol in drinking water, both F344/N rats and B63F1 mice showed negative effects. The range of exposure for the two species was between 70 mg/kg body weight per day to 1300 mg/kg body weight per day. Decreased body weight and water consumption were seen for both species. Rats had reduced red blood cell counts and thymus weights, as well as lesions in the liver, spleen, and bone marrow. [25] Regulation in Canada [ edit ]

Environment and Health Canada recommended that 2-butoxyethanol be added to Schedule 1 of the Canadian Environmental Protection Act, 1999 (CEPA). [27] Under these regulations gas efficient cars 2012, products containing 2-butoxyethanol are to be diluted below a certain concentration. Only those in which the user performs the required dilution are required to include it on labelling information. [28] Regulation in the US [ edit ]

It is approved by the Food and Drug Administration as an indirect and direct food additive for use as an antimicrobial agent, defoamer, stabilizer and component of adhesives., [10] and also may be used to wash or assist in the peeling of fruits and vegetables and may be safely used as components of articles intended for use in packaging, transporting holding food. [31] After it was deleted from a UN list of substances requiring special toxicity labeling in 1994, and a subsequent petition by the American Chemistry Council electricity and circuits class 6 pdf, 2-Butoxyethanol was removed from the U.S. Environmental Protection Agency’s list of hazardous air pollutants in 2004. [32] [33] The EPA currently lists it in the context of pesticides as a potentially toxic inert, with high priority for testing. [34] The safety of products containing 2-Butoxyethanol as normally used is defended by the industry trade groups the American Chemistry Council [33] and the Soap and Detergent Association.