Creutzfeldt–jakob disease – simple english wikipedia, the free encyclopedia gas variables pogil extension questions


This form of CJD is usually caused by a medical procedure where a person gets blood or tissue from someone with CJD. For example, if a person can get iatrogenic CJD if they get a blood transfusion or a cornea transplant from someone who has CJD. [7] Signs and symptoms [ change | change source ]

Most people with CJD die within six months after their first symptoms appeared. Often, they die of pneumonia caused by trouble coughing. About 15% of patients survive for two or more years. [12] Some patients have lived 4–5 years with mostly mental symptoms, until the disease gets worse and causes more physical symptoms. Once this happens, people usually die within a year. [12]

The symptoms of CJD are caused by the death of more and more of the brain’s nerve cells. When scientists look at brain tissue from a CJD patient under a microscope, they can see many tiny holes where whole areas of nerve cells have died. Diagnosis [ change | change source ]

Doctors may suspect CJD when a person has certain symptoms. For example, dementia usually gets worse slowly. Dementia that gets worse very quickly is unusual. Along with symptoms like jerky movements, these symptoms may point to possible CJD. [13]

• Electroencephalography (EEG): This test that shows the electrical activity in the brain. A doctor will often be able to see changes on the EEG that are common in people with CJD. The type of changes that show on the EEG will depend on the type of CJD the patient has, and how far along their disease is. [15]

• Biopsy: To do a biopsy, a surgeon uses a needle to take a small piece of tissue from the body, so doctors can look at it under a microscope. vCJD can be diagnosed with a biopsy of the tonsils. For all of the other types of CJD, a biopsy of the brain is the only way to tell for sure if a person has CJD. However, since a biopsy of the brain can cause brain damage, a brain biopsy is usually not done if other tests have already shown that a person probably has CJD. [14]

Today, the only treatments for CJD are medicines that treat the disease’s symptoms and help patients be more comfortable. For example, patients who have seizures may be given anticonvulsant medications. Benzodiazepines can make muscle jerks happen less often. [12]

Patients may also choose to have medical procedures to help with bad symptoms. For example, CJD may cause so much trouble swallowing that a person cannot eat. Some people with CJD choose to have a feeding tube put in when they can no longer eat. [16] This is a tube that goes into the stomach, so that special liquid can be given right into the stomach to give the person nutrition. Related pages [ change | change source ]

• ↑ VeriMed Healthcare Network, reviewed by: David C. Dugdale, Luc Jasmin,David Zieve (2011-09-26). "Creutzfeldt–Jakob disease: Transmissible spongiform encephalopathy; vCJD; CJD; Jacob-Creutzfeldt disease". U.S. National Library of Medicine . Retrieved 2012-04-25. CS1 maint: Multiple names: authors list ( link)

• ↑ Ironside, JW; Sutherland, K; Bell, JE; McCardle, L; Barrie, C; Estebeiro, K; Zeidler, M; Will, RG (1996). "A new variant of Creutzfeldt–Jakob disease: neuropathological and clinical features.". Cold Spring Harbor symposia on quantitative biology 61: 523–30. doi: 10.1101/SQB.1996.061.01.052. PMID 9246478.

• ↑ Niimi Y, Iwasaki Y, Umemura T (December 2008). "MM2-cortical-type sporadic Creutzfeldt–Jakob disease with early stage cerebral cortical pathology presenting with a rapidly progressive clinical course". Neuropathology 28 (6): 645–51. doi: 10.1111/j.1440-1789.2008.00904.x. PMID 18410280 .

• ↑ Lugaresi, E; Medori, R; Montagna, P; Baruzzi, A; Cortelli, P; Lugaresi, A; Tinuper, P; Zucconi, M et al. (Oct 16, 1986). "Fatal familial insomnia and dysautonomia with selective degeneration of thalamic nuclei". The New England Journal of Medicine 315 (16): 997–1003. doi: 10.1056/NEJM198610163151605. PMID 3762620.

• ↑ Murray ED, Buttner N, Price BH. (2012) Depression and Psychosis in Neurological Practice. In: Neurology in Clinical Practice, 6th Edition. Bradley WG, Daroff RB, Fenichel GM, Jankovic J (eds.) Butterworth Heinemann. April 12, 2012. ISBN 1437704344 | ISBN 978-1437704341

• ↑ 14.0 14.1 14.2 14.3 Manix M; Kalakoti P; ‘’et al.’’ (November 2015). "Creutzfeldt-Jakob disease: Updated diagnostic criteria, treatment algorithm, and the utility of brain biopsy". Neurosurgery Focus 39 (5). doi: 10.3171/2015.8.FOCUS15328 . . Retrieved January 20, 2016.