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Chromium is known to help increase lean muscle mass, promote fat loss and reduce food intake through its appetite suppressing properties. Chromium poses minimal risks to the human body in low doses (25–45 micrograms a day for adults). Higher doses may cause headaches, and watery stools or constipation are possible. Garcinia cambogia

Garcinia Cambogia is another natural weight loss supplement that utilizes the active ingredient in the fruit’s rind, hydroxycitric acid, or HCA. HCA is thought to boost fat-burning efforts and helps reduce appetite. HCA blocks the enzyme called citrate lyase, which the body uses to make fat. HCA also raises levels of the brain chemical serotonin, which may make one feel less hungry. Guarana

Guarana has among the highest concentrations of caffeine in any plant; containing up to 3.5 percent to 5.8 percent caffeine by volume (compared to a cup of coffee at 2%). Users can consume up to 800 milligrams of guarana a day for increased energy performance. Side effects include difficulty sleeping, indigestion, anxiety, changes in blood pressure, dependence and a quickened heartbeat. Guarana is known to interact with medicines like some antidepressants, lithium, sedatives, other stimulants and blood thinners. Saffron Extract

In controlled trials published in the Journal of Integrative Medicine, a large effect size was discovered for saffron supplementation versus placebo in treatment for depressive symptoms (M ES = 1.62, P  .05) had not been observed. Neither the acute coffee nor the caffeine anhydrous improved strength more than the placebo. It was concluded that coffee and caffeine anhydrous might be a suitable pre-exercise sources of caffeine for high-intensity workouts. [2] Amla Extract

Preclinical studies have exhibited that amla extract contains analgesic, antipyretic, antiatherogenic, antitussive, gastroprotective, cardioprotective, adaptogenic, antianemia, wound healing, antihypercholesterolemic, antiatherosclerotic, antidiarrheal, nephroprotective, hepatoprotective, and neuroprotective properties. Experimental studies have also pointed out that amla and some of its phytochemicals also harness possess antineoplastic effects. In additional reports, amla was said to contain chemomodulatory, radiomodulatory, anti-inflammatory, chemopreventive effects, antioxidant, free radical scavenging, antimutagenic and immunomodulatory activities, which are properties that are useful in treating and in the prevention of cancer. [3] Cayenne Pepper

Cayenne pepper is a red pepper, or a chili pepper. It is commonly used in cuisine to add heat and flavor to dishes. According to WebMD, cayenne pepper “may help burn calories and curb appetite, especially in people who aren’t used to eating it.”

According to a study published in Physiology & Behavior, “The appetite responses were different between those who liked red pepper and those who did not, suggesting that when the stimulus is unfamiliar it has a greater effect.” Study results indicate that once a person becomes used to spicy food, the effect wears off, but further study is needed to determine when the effect stops working. The study showed those who ate a half a teaspoon of the pepper either before or mixed with their meal burned 10 more calories over a four hour period than those who did not, so the results are small. Yohimbe Extract

Yombimbe is a tree native to Nigeria, Cameroon, and the Congo. Its bark is used for medicinal purposes. The tree may be endangered as a result of overharvesting. According to the University of Michigan, it is supposed to help weight-loss by boosting metabolism, suppressing the appetite, and increasing fat burning through stimulation of the nervous system.

Research on yohimbe and weight-loss is limited. However, a systematic review of multiple supplements published in the American Journal of Clinical Nutrition revealed that yohimbe, along with various other supplements marketed to dieters don’t have convincing data to support them. “None of the reviewed dietary supplements can be recommended for over-the-counter use.” [4] L-Theanine

L-Theanine, also known as theanine, is an amino acid [a building block of protein] found in green tea. Its chemical structure is similar to glutamate, a naturally occurring amino acid that helps the body transmit nerve impulses to the brain. Theanine had been used for treating “anxiety, high blood pressure, for preventing Alzhimer’s disease, and for making cancer drugs more effective.” That’s not to say science supports these claims.

According to the U.S. National Library of Medicine, theanine may be effective for treating some metabolic disorders (genetic in nature). There’s no strong connection to weight-loss or athletic performance. Also: read our Burn HD Weight-Loss Kit review »