New paper on gwas scientific clearing house gas finder app


To infer that a single-nucleotide polymorphism (SNP) either affects a phenotype or is linkage disequilibrium with a causal site, we must have some assurance that any SNP-phenotype correlation is not the result of confounding with environmental variables that also affect the trait. electricity wiki In this study, we study the properties of linkage disequilibrium (LD) Score regression, a recently developed method for using summary statistics from genome-wide association studies to ensure that confounding does not inflate the number of false positives. We do not treat the effects of genetic variation as a random variable and thus are able to obtain results about the unbiasedness of this method. We demonstrate that LD Score regression can produce estimates of confounding at null SNPs that are unbiased or conservative under fairly general conditions. This robustness holds in the case of the parent genotype affecting the offspring phenotype through some environmental mechanism, despite the resulting correlation over SNPs between LD Scores and the degree of confounding. gas vs electric oven for baking cakes Additionally, we demonstrate that LD Score regression can produce reasonably robust estimates of the genetic correlation, even when its estimates of the genetic covariance and the two univariate heritabilities are substantially biased.

If you like couch surfing tourism look up the youtube video ‘a tour of streater North dakota’ . Surprisingly its not well known even though its one of the largest cities in the world and set amidst the highest mountains in the world. gas variables pogil worksheet answers Makes Beijing and the Himalayas look like a trailer park set in a hilly area created by garbage dumps–there is a garbage dump in prince william county that looks like a mountain. gaston y daniela While Beijing has an institute named for C N Yang , streater has a house named after one of the Roosevelts.

(Bemidji is near a native american reservation where they had one of those mass school shootings—alot of depressed, alcoholic and dope addicted indians up there–some of my relatives viewed the native americans as worthless, lazy scum–perhaps genetically inferior or defective. Back in 1862 most of the native americans were removed from minnesota (except the ones who were killed–called the Dakota war of 1862 ) and sent to south and north dakota to find a job. list of electricity usage by appliances They were just lazy homeless people in Minnesota, getting free food like wild rice using their food stamps. I once took my grandma on a ‘swamp walk’ somewhere in MN to see the beavers and tamarack (larch) trees –i thought she would enjoy it–she lost her shoes in the mud. ).

Some became mormons and got jobs at Hewlett Packard—ND didnt have that fracked oil then so they wanted to find a job which mormons gave them for a price–you have to do missionary work, and maybe donate some of your children to work for the church. Get rid of all that global warming nonsense, and focus on real work ,like selling off the national parks to Exxon.

In Denver some worked for the water dept in denver, and some became doctor and psychiatrists. (I think originally they wanted to help cure gay people, but they dropped that pretty fast–ND brethren religion is not used in psychiatry.) They lived right near those 2 mass shootings in Denver area—the film ‘bowling for columbine’ by michael moore describes one, and then there was one at a batman movie by a PhD student in neuroscience –and some of my friends and relatives were in that same MD/PhD program.

(Social network theorist Granoveter has the ‘6 degrees of freedom’ idea (or ‘lose connections’ or ‘weak ties’. So i am weakly tied to about 5 mass shootings or massacres (minnesota 2, colorado 2, connecticut 1). I could throw in Va Tech where they had one since i am familiar with that area. (I was slightly aquainted with a few people in their economics and mathematical biology depts –one had a PhD from MIT he got under Robert Solow, and got kicked out for teaching his classes under influence of LSD. Most of those people i met in WV since i tend to stay on the other side of the border. gas after eating eggs Buchanan, Tideman, Cresswell were at VT–i only met Tideman. He gave me a book which i was supposed to return but didn’t get around to it–i hit the road and ran up to the mountains. ). A popular writer Johann Hari (has a book called ‘lost connections’ and another ‘chasing the scream’) discussed that paper by a UBC psychologisdt (his paper was rejected by Science and Nature–i just renewed my AAAS sub today though i can’t afford it nor have time to read it). Thats a different view than GWAS.