The best time to take your thyroid medication youtube gas monkey

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The researchers found that the patients taking nighttime levothyroxine had a drop in TSH of 1.25 mU/L, a significant change. The free thyroxine ( free T4) level went up by 0.07 ng/dL, and total triiodothyronine (total T3) went up by 6.5 ng/dL. There were no significant changes in the other factors measured.

In the end, though, it’s important to talk with your doctor about changing the time to take your generic levothyroxine or brand name levothyroxine (for example, Synthroid). If you and your doctor decide to give it a go and take your thyroid medication in the evening, be sure to have your thyroid levels evaluated (six to eight weeks is a reasonable timeframe) after you’ve made the switch.

The blood test results, along with any improvements or worsening of symptoms, will help you and your doctor determine if you need to adjust the dosage or revert back to taking your medication in the early morning Important Point to Keep in Mind: Studies Only Evaluated Levothyroxine

Thyroid drugs that contain T3—such as Cytomel, and the natural desiccated thyroid drugs like Nature-throid and Armour Thyroid—are used directly by the body within hours. These drugs were not evaluated in the study, and it’s not known if medications containing T3, or natural desiccated thyroid drugs would be better absorbed at night.

Anecdotally, some thyroid patients have reported improvement in symptoms when taking some or all of their T3-based thyroid hormone replacement medications in the evening. But some thyroid patients also find that if they take a medication with T3 later in the day or in the evening, the slight stimulatory effect of the T3 medication can make it difficult to sleep.

So keep in mind that while it’s possible that if similar studies were conducted with T3 drugs, the results would be similar, but there is a chance that it would impact sleep quality in some patients. You should only make such a change after discussing it with your doctor.

Some doctors have suggested that patients who take T3 medications use a time-released or sustained release formulation of T3, or split their doses and take their medication several times throughout the day. This approach seems to minimize sleep interference; however, again, be sure to only change the dosing under the guidance of your doctor.

Again, if you do make a change to how you take your T3 thyroid medication, you’ll want to have a reevaluation of blood levels and symptoms after several weeks, to determine if you need to adjust the dosage or timing of your medication. A Word From Verywell

While standard guidelines suggest taking your thyroid hormone treatment first thing in the morning on an empty stomach (due to the risk of food interfering with absorption), taking your thyroid medication in the evening may be sensible in some cases.

Bach-Huynh TG, Nayak, B. Loh J, Soldin S, Jonklaas J. Timing of Levothyroxine Administration Affects Serum Thyrotropin Concentration. Journal of Clinical Endocrinology and Metabolism. 2009 Oct; 94(10): 3905–3912. Published online 2009 Jul 7. doi: 10.1210/jc.2009-0860

Rajput, R Chatterjee S, Rajput M. Can Levothyroxine Be Taken as Evening Dose? Comparative Evaluation of Morning versus Evening Dose of Levothyroxine in Treatment of Hypothyroidism. Journal of Thyroid Research. 2011;2011:505239. doi: 10.4061/2011/505239. Epub 2011 Jul 14.